The AEVIOM Journal
The science of cellular longevity, explained without shortcuts: mechanisms, studies, sources.
How to Choose a Supplement When Marketing Proves Nothing
The supplement market runs largely on image and influence. Regulation, meanwhile, draws a sharp line between what is proven and what is merely claimed.
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Pilates stops. So does the spa. Your cells don't.
Lifestyle·7 min·EFSA · Journal of the International Society of Sports NutritionSunday evening. You put away the robe, your suitcase from the spa week is already packed....
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The Longevity Hotel: When Luxury Becomes a Biological Intervention
Clinique La Prairie, Lanserhof, Büchinger Wilhelmi, SHA Wellness: these establishments measure your biological age and build protocols around the Hallmarks of Aging. What geroscience says about...
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Collagen: Which Type, What Dose, and Why It Actually Matters
Not all collagen capsules are the same. The type matters, the size of the molecule matters, the dose matters. And the question doesn't start at 80:...
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NR or NMN: The NAD+ Precursor With a Ten-Year Head Start
Both molecules promise the same thing: raising NAD+. But one began human trials in 2016, while the other was still at its first ten-person trial in...
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Collagen and Vitamin C: A Good Match?
You'll often find them side by side on a label. Marketing coincidence, or real biological logic? The answer runs through a trial against scurvy, a genetic...
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Citrulline and L-Carnitine: What Watermelon and Steak Hide
Two complicated names, two very familiar origins: watermelon and meat. Where do citrulline and L-carnitine come from, what do they do in the body, and what...
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Creatine: Far More Than a Gym Supplement
People assume it is only for bodybuilders. Yet it is a molecule your body makes every day, one of the most studied in nutrition, and researchers...
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Compléments longévité : lesquels ont vraiment des preuves chez l'humain ?
NAD+, créatine, CoQ10, oméga-3... Quels compléments longévité ont vraiment des preuves chez l'humain, et lesquels restent prometteurs mais précoces.
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NAD+, CoQ10, créatine : la science de l'énergie cellulaire
NAD+, CoQ10, créatine, L-carnitine : quels actifs ont vraiment des données sur l'énergie cellulaire, et à quelles doses.
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NAD+: What Research Tells Us About How It Changes With Age
NAD+ takes part in more than 500 biological reactions. Research examines how its levels change over the course of life and its role in the mechanisms...
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The Epigenetic Clock: Can Science Really Measure Your Biological Age?
Since Steve Horvath in 2013, science can measure real biological age through DNA methylation. The Horvath clock, GrimAge, DunedinPACE, and their link to NAD+.
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Zombie Cells: How Cellular Senescence and Inflammaging Accelerate Aging
Cells that refuse to die secrete a pro-inflammatory cocktail that poisons tissue. Cellular senescence, SASP and inflammaging explained by geroscience.
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Homocysteine: The Molecule Four Nutrients Are Always Working to Neutralize
You've probably never heard of it, yet your body makes it every moment. The story begins with a medical mystery left unanswered for thirty years, and...
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Why Women Live Longer: The Cell Biology of Sex-Based Aging
The X chromosome, maternal mitochondria, menopause and the epigenome, sex-based immunosenescence: cell biology explains why men and women age differently.
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Gut Microbiome and Longevity: What Centenarians Have in Common
The gut microbiome is a 1-2 kg organ whose composition governs inflammation, immunity and longevity. Akkermansia muciniphila, dysbiosis, urolithin A.
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The Circadian Clock and Aging: What Studies Say About Biological Rhythm
2017 Nobel Prize: what studies say about the molecular mechanisms of the circadian clock and how they change with age.
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What the World's Oldest Animals Teach Us About the Biology of Longevity
A 200-year-old bowhead whale, the naked mole-rat, a 400-year-old Greenland shark, the tardigrade, the immortal jellyfish: what the longest-lived animals teach geroscience.
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The Blue Zones: What the World's Longest-Living Populations Teach Us About the Biology of Aging
Sardinia, Okinawa, Loma Linda, Nicoya, Ikaria: five populations that, without modern medicine, solved part of biological aging. What geroscience takes from them.
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NAD+ and Coenzyme Q10: Two Molecules Studied in Mitochondrial Biology
NAD+ and CoQ10 act at consecutive steps of the mitochondrial respiratory chain. This article describes their respective roles as documented by cell biology.
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5 Habits That Accelerate Biological Aging
Genetics accounts for only 20-30% of biological longevity. Five daily habits measurably accelerate cellular aging — here are the mechanisms documented by science.
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Exercise and Cellular Aging: What Biology Really Says
Exercise is the best-documented longevity intervention in medicine. Cell biology has decoded its precise mechanisms, from NAD+ to telomeres, mitochondria to the epigenome.
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Mitochondria and Aging: What Studies Observe About Cellular Energy Production
Mitochondrial dysfunction is one of the most studied mechanisms of biological aging. This article looks at what research observes about how mitochondrial efficiency changes over the...
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The Hallmarks of Aging: The Scientific Framework That Unified Aging Biology
In 2013 and again in 2023, López-Otín et al. laid out in Cell the reference framework for cellular aging: twelve mechanisms, three categories, one shared language...
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